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作者:余佳佑
作者(英文):Chia-Yu Yu
論文名稱:以跨顱磁刺激影響腦區與道德判斷並檢視個人化與人稱變項之關係
論文名稱(英文):Using transcranial magnetic stimulation on rTPJ and rDLPFC to influence the personalization and person-perspective variables in moral judgment
指導教授:周育如
指導教授(英文):Yu-Ju Chou
口試委員:袁宗凡
劉効樺
口試委員(英文):Zung-Fan Yuan
Shiau-Hua Liu
學位類別:碩士
校院名稱:國立東華大學
系所名稱:諮商與臨床心理學系
學號:610783020
出版年(民國):109
畢業學年度:109
語文別:中文
論文頁數:118
關鍵詞:道德判斷個人化人稱跨顱磁刺激右側背外側前額葉皮質右側頂顳葉交界處
關鍵詞(英文):Moral judgmentPersonalizationPersonal-perspectiveTranscranial magnetic stimulationrDLPFCrTPJ
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不同的腦區功能,可能影響著人們有不同的道德判斷。首先,透過故事是否「個人化」與講述故事的「人稱」觀點變項來分類各種不同道德情境,在閱讀故事並作出道德判斷的同時,利用跨顱磁刺激(Transcranial magnetic stimulation, TMS)作用於腦區的右側背外側前額皮質(right dorsolateral prefrontal cortex, r-DLPFC)以及右側頂顳葉交界處(right temporoparietal junction, r-TPJ),檢視此二腦區受磁波干擾之後會如何影響道德判斷。
本研究共招募32名研究參與者,男女各半。實驗使用「個人化」變項的個人(personal)與非個人(impersonal)故事,分別搭配「人稱」變項的第一人稱(first-person perspectives, 1PP)與第三人稱(third-person perspectives, 3PP)視角,共四種道德故事類別,將施打有磁波的real TMS與無磁波的sham TMS於腦區r-DLPFC或r-TPJ,檢視道德評分與反應時間的變化。
結果顯示:第一、道德判斷是極細緻的判斷選擇,在道德兩難情境裡,參與者給出「不合適」的答案裡,其實有著偏向「稍微不合適」與「更不合適」的顯著層次差異。第二、當磁波影響腦區後,發現個人化與人稱變項之間存在著交互作用,也就是磁波影響嚴重程度較大傷害的personal情境,不論以第一人稱或第三人稱觀點,都會從「嚴格」轉變成「寬容」的道德評分;嚴重程度較小傷害的impersonal情境,則僅影響第三人稱觀點同樣從「嚴格」轉變成「寬容」。第三、TMS作用於r-TPJ腦區對道德判斷的影響較大,相較於r-DLPFC腦區,TMS使四類道德情境的其中三類的道德分數產生顯著變化。第四、磁波影響作答速度有加快情形,但若僅分析2,501毫秒TMS刺激後才下決策的數據,則反應時間僅幾近顯著的水準。
Moral judgments involved multiple brain regions and associated with different types of moral dilemmas. This study aims to manipulate the variables of "Personalization" and "Personal-perspective" in moral stories and disrupted two brain regions by TMS to inspect the causal roles of the these factors in moral judgement.
Method. A total of 32 participants were recruited in this study, half males and half females. There are two variables of moral stories, "Personalization" and "Personal-perspective", each comprising two levels, personal and impersonal, first-person perspective (1PP) and third-person perspective (3PP). While participants were reading stories and making moral judgments, a non-invasive Transcranial Magnetic Stimulation (TMS) was discharged to influence the right dorsolateral prefrontal cortex (r-DLPFC) or the right temporoparietal junction (r-TPJ). Then, the experiment analyzed the changes of moral scores and reaction time (RT) with the randomly application of real and sham TMS.
Result. Result. First, moral judgment was a sophisticated mechanism, as "Inappropriate" might stand for "slight inappropriate" or "more inappropriate". Secondly, with TMS condition, there was an interaction between Personalization and Personal-perspective. While personal stories with severe harm presented moral score changes and the tendency of being "more tolerant" towards both self and others, impersonal stories with minor harm only presented the same tendency towards others. Thirdly, TMS on the r-TPJ had greater influence on moral judgments, compared with on the r-DLPFC. Last, it was found that TMS accelerated moral judgment. However, if only the data of moral judgments longer than 2,501 milliseconds were analyzed, the TMS effect on RT reached merely marginal significance.
第一章 緒論  1
第一節 研究動機與背景  1
第二節 多元的腦區功能影響道德判斷  3
一、背外側前額葉皮質─道德決策、利益與公平  3
二、頂顳葉交界處─心智理論  4
三、其他腦區─情緒、情節記憶調節  6
第三節 腦區如何影響道德判斷  10
一、不同故事情境下的道德判斷  10
二、腦區功能差異影響道德判斷  10
三、道德判斷之「己者」對於「他者」的信念  11
四、跨顱磁刺激影響腦區進行道德判斷  11
五、不同人稱視角的道德判斷差異  12
六、改變信念也可能造成道德判斷改變  12
第四節 影響道德判斷的因素  13
一、不同道德故事情境的因素(個人化、人稱)  13
二、磁波影響腦區進行道德判斷(腦區、TMS)  14
第五節 測量變項的選擇:道德評分與反應時間  15
一、道德判斷的反應差異  15
二、從道德直覺的思考到行為判斷  15
三、道德判斷可能是多種因素的交互影響結果  16
第二章 研究目的、問題、假設  17
第一節 目的  17
第二節 問題  17
第三節 假設  18
第三章 方法  19
第一節 研究參與者  19
第二節 研究材料與設備  19
一、材料  19
二、設備  21
第三節 實驗設計  22
一、變項與實驗分組  22
二、實驗程序  23
三、TMS參數  26
四、腦區定位方式  27
第四節 資料分析方法  31
第四章 研究結果  32
第一節 分析一結果  32
一、分析一之依參與者分析─四個變項整體分析  32
二、分析一之依項目分析─四個變項整體分析  42
第二節 分析二結果  47
一、分析二之依參與者分析─ r-DLPFC組  47
二、分析二之依項目分析─ r-DLPFC組  54
三、分析二之依參與者分析─ r-TPJ組  56
四、分析二之依項目分析─ r-TPJ組  68
第三節 分析三結果  70
一、分析三之依項目分析─四個變項整體分析(2,501至20,000毫秒數據)  70
二、分析三之依項目分析─ r-DLPFC組(2,501至20,000毫秒數據)  73
三、分析三之依項目分析─ r-TPJ組(2,501至20,000毫秒數據)  76
第五章 討論與結論  77
第一節 分析一討論  77
一、依參與者分析  77
二、依項目分析  82
第二節 分析二討論  83
一、依參與者分析─ r-DLPFC組  83
二、依項目分析─ r-DLPFC組  85
三、依參與者分析─ r-TPJ組  85
四、依項目分析─ r-TPJ組  87
第三節 分析三討論  88
一、依項目分析─四個變項整體分析(2,501至20,000毫秒數據)  88
二、依項目分析─ r-DLPFC組(2,501至20,000毫秒數據)  89
三、依項目分析─ r-TPJ組(2,501至20,000毫秒數據)  90
第四節 綜合討論與結論  92
一、綜合討論  92
二、研究限制  97
三、未來應用  99
第五節 總結論  101
一、不同故事類別之間的道德判斷差異  101
二、在磁波作用下,影響腦區對閱讀不同類別的故事進行道德判斷  102
三、細緻化的道德判斷  103
參考文獻  104
附錄  110
附錄一 故事材料範例  110
附錄二 參與者招募文宣  115
附錄三 左右手檢測評估量表  116
附錄四 IRB審查核可證明  117
附錄五 腦區定位標記步驟  118
中文參考文獻:
陳姿妤(2017)。以跨顱磁刺激影響道德判斷(未出版之碩士論文)。國立東華大學,花蓮縣。
外文參考文獻:
Allman, J., Hakeem, A., & Watson, K. (2002). Book Review: Two Phylogenetic Specializations in the Human Brain. The Neuroscientist, 8(4),335-346. doi:10.1177/107385840200800409
Anderson, S. W., Bechara, A., Damasio, H., Tranel, D., & Damasio, A. R. (1999). Impairment of social and moral behavior related to early damage in human prefrontal cortex. Nature Neuroscience, 2(11), 1032–1037. doi:10.1038/14833
Avram, M., Hennig-Fast, K., Bao, Y., Pöppel, E., Reiser, M., Blautzik, J., Giordano, J., Gutyrchik, E. (2014). Neural correlates of moral judgments in first- and third-person perspectives: implications for neuroethics and beyond. BMC Neuroscience, 15(1), 39. doi:10.1186/1471-2202-15-39
Barraclough, D. J., Conroy, M. L., & Lee, D. (2004). Prefrontal cortex and decision making in a mixed-strategy game. Nature Neuroscience, 7(4), 404–410. doi:10.1038/nn1209
Bargh, J. A., & Chartrand, T. L. (1999). The unbearable automaticity of being. American Psychologist, 54(7), 462–479. doi:10.1037/0003-066x.54.7.462
Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994). Insensitivity to future consequences following damage to human prefrontal cortex. Cognition, 50(1-3), 7–15. doi:10.1016/0010-0277(94)90018-3
Beam, W., Borckardt, J. J., Reeves, S. T., & George, M. S. (2009). An efficient and accurate new method for locating the F3 position for prefrontal TMS applications. Brain Stimulation, 2(1), 50–54. doi:10.1016/j.brs.2008.09.006
Blair, R. (1995). A cognitive developmental approach to morality: investigating the psychopath. Cognition, 57(1), 1–29. doi:10.1016/0010-0277(95)00676-p
Costa, A., Torriero, S., Oliveri, M., Caltagirone, C. (2008). Prefrontal and Temporo-Parietal Involvement in Taking Others’ Perspective: TMS Evidence. Behavioural Neurology, 19(1-2), 71–74. doi:10.1155/2008/694632
Damasio, H; Grabowski, T; Frank, R; Galaburda, A.; Damasio, A. (1994). The return of Phineas Gage: clues about the brain from the skull of a famous patient. Science, 264(5162), 1102–1105. doi:10.1126/science.8178168
Eslinger, P. J., Grattan, L. M., Damasio, H., & Damasio, A. R. (1992). Developmental Consequences of Childhood Frontal Lobe Damage. Archives of Neurology, 49(7), 764–769.doi:10.1001/archneur.1992.0053031011
Frith, U., & Frith, C. D. (2003). Development and neurophysiology of mentalizing. Philosophical Transactions of the Royal Society B: Biological Sciences, 358(1431), 459–473. doi:10.1098/rstb.2002.1218
Glenn, A. L., Raine, A., Schug, R. A., Young, L., & Hauser, M. (2009). Increased DLPFC activity during moral decision-making in psychopathy. Molecular Psychiatry, 14(10), 909–911.doi:10.1038/mp.2009.76
Goel, V., Eimontaite, I., Goel, A., & Schindler, I. (2015). Differential Modulation of Performance in Insight and Divergent Thinking Tasks with tDCS. The Journal of Problem Solving, 8(1), 23–35. doi: 10.7771/1932-6246.1172
Greene, J. D. (2001). An fMRI Investigation of Emotional Engagement in Moral Judgment. Science, 293(5537), 2105–2108.doi:10.1126/science.1062872
Greene, J. D. (2003). From neural “is” to moral “ought”: what are the moral implications of neuroscientific moral psychology? Nature Reviews Neuroscience, 4(10), 846–850. doi:10.1038/nrn1224
Greene, J. D., Morelli, S. A., Lowenberg, K., Nystrom, L. E., & Cohen, J. D. (2008). Cognitive load selectively interferes with utilitarian moral judgment. Cognition, 107(3), 1144–1154. doi:10.1016/j.cognition.2007. 11.004.
Haidt, J. (2001). The emotional dog and its rational tail: A social intuitionist approach to moral judgment. Psychological Review, 108(4), 814–834. doi:10.1037/0033-295x.108.4.814
Heekeren, H. R., Wartenburger, I., Schmidt, H., Prehn, K., Schwintowski, H.-P., & Villringer, A. (2005). Influence of bodily harm on neural correlates of semantic and moral decision-making. NeuroImage, 24(3), 887–897.doi:10.1016/j.neuroimage.2004.09.026
Herwig, U., Satrapi, P., & Schönfeldt-Lecuona, C. (2003). Using the International 10-20 EEG System for Positioning of Transcranial Magnetic Stimulation. Brain Topography, 16(2), 95–99. doi:10.1023/b:brat.0000006333.93597.9d
Jasper, H. H. (1958).The Ten-twenty Electrode Systems of the International Federation. Electroencephalography and Clinical Neurophysiology.10(2), 371-375. doi:10.1016/0013-4694(58)90053-1.
Jeurissen, D., Sack, A. T., Roebroeck, A., Russ, B. E., & Pascual-Leone, A. (2014). TMS affects moral judgment, showing the role of DLPFC and TPJ in cognitive and emotional processing. Frontiers in Neuroscience, 8(18).doi:10.3389/fnins.2014.00018
Johnson, T., Kulesa, P., Cho, Y. I., & Shavitt, S. (2005). The Relation Between Culture and Response Styles. Journal of Cross-Cultural Psychology, 36(2), 264–277. doi:10.1177/0022022104272905
Jurcak, V., Tsuzuki, D., & Dan, I. (2007). 10/20, 10/10, and 10/5 systems revisited: Their validity as relative head-surface-based positioning systems. NeuroImage, 34(4), 1600–1611. doi:10.1016/j.neuroimage.2006.09.024
Knoch D, Pascual-Leone A, Meyer K, Treyer V, Fehr E. (2006). Diminishing reciprocal fairness by disrupting the right prefrontal cortex. Science, 314(5800), 829–32. doi:10.1126/science.1129156
Kratz, O., Studer, P., Barth, W., Wangler, S., Hoegl, T., Heinrich, H., & Moll, G. H. (2011). Seizure in a Nonpredisposed Individual Induced by Single-Pulse Transcranial Magnetic Stimulation. The Journal of ECT, 27(1), 48–50. doi:10.1097/yct.0b013e3181d2ef85
Krall, S. C., Volz, L. J., Oberwelland, E., Grefkes, C., Fink, G. R., & Konrad, K. (2016). The right temporoparietal junction in attention and social interaction: A transcranial magnetic stimulation study. Human Brain Mapping, 37(2), 796–807. doi:10.1002/hbm.23068
Lane, R. D., Chua, P. M.-L., & Dolan, R. J. (1999). Common effects of emotional valence, arousal and attention on neural activation during visual processing of pictures. Neuropsychologia, 37(9), 989–997. doi:10.1016/s0028-3932(99)00017-2
Lo Gerfo, E., Gallucci, A., Morese, R., Vergallito, A., Ottone, S., Ponzano, F., Locatelli, G., Bosco, F., Josefina, L., Lauro, R. (2019). The role of ventromedial prefrontal cortex and temporo-parietal junction in third-party punishment behavior. NeuroImage, 200(15), 501–510. doi:10.1016/j.neuroimage.2019.06.047
MacIntyre, A. (1984). After virtue: a study in moral theory (2nd ed.). Notre Dame, Ind:University of Notre Dame Press.
Martin, A. K., Huang, J., & Meinzer, M. (2018). Dissociable roles for the rTPJ and dmPFC in self-other processing: a HD-tDCS study. bioRxiv. doi.org/10.1101/306183
Malmivuo, J., Plonsey, R. (1995). Bioelectromagnetism-principles and applications of bioelectric and biomagnetic fields (Illustrated). New York, Oxford University Press.
Machii, K., Cohen, D., Ramos-Estebanez, C., & Pascual-Leone, A. (2006). Safety of rTMS to non-motor cortical areas in healthy participants and patients. Clinical Neurophysiology, 117(2), 455–471. doi:10.1016/j.clinph.2005.10.014
Mai, X., Zhang, W., Hu, X., Zhen, Z., Xu, Z., Zhang, J., & Liu, C. (2016). Using tDCS to Explore the Role of the Right Temporo-Parietal Junction in Theory of Mind and Cognitive Empathy. Frontiers in Psychology, 7(380). 1–7. doi:10.3389/fpsyg.2016.00380
McGuire, J., Langdon, R., Coltheart, M., & Mackenzie, C. (2009). A reanalysis of the personal/impersonal distinction in moral psychology research. Journal of Experimental Social Psychology, 45(3), 577–580. doi:10.1016/j.jesp.2009.01.002
Moll, J., de Oliveira-Souza, R., Bramati, I. E., & Grafman, J. (2002a). Functional Networks in Emotional Moral and Nonmoral Social Judgments. NeuroImage, 16(3), 696–703. doi:10.1006/nimg.2002.1118
Moll, J., de Oliveira-Souza, R., Eslinger, P. J., Bramati, I. E., Mourão-Miranda, J., Andreiuolo, P. A., & Pessoa, L. (2002b). The Neural Correlates of Moral Sensitivity: A Functional Magnetic Resonance Imaging Investigation of Basic and Moral Emotions. The Journal of Neuroscience, 22(7), 2730–2736. doi:10.1523/jneurosci.22-07-02730.2002
Moll, J., de Oliveira-Souza, R., & Eslinger, P. J. (2003). Morals and the human brain: a working model. NeuroReport, 22(7), 299–305. doi:10.1097/00001756-200303030-00001
Moll, J., Zahn, R., de Oliveira-Souza, R., Krueger, F., & Grafman, J. (2005). The neural basis of human moral cognition. Nat. Rev. Neurosci., 6, 799–809. doi: 10.1038/nrn1768
Najib, U., & Horvath, J. C. (2014). Transcranial Magnetic Stimulation (TMS) Safety Considerations and Recommendations. Neuromethods, 89, 15–30. doi:10.1007/978-1-4939-0879-0_2
Oldfield, R. C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9(1), 97–113. doi:10.1016/0028-3932(71)90067-4
Perner, J., & Wimmer, H. (1985). “John thinks that Mary thinks that…” attribution of second-order beliefs by 5- to 10-year-old children. Journal of Experimental Child Psychology, 39(3), 437–471. doi:10.1016/0022-0965(85)90051-7
Rozin P, Loewry L, Imada S, Haidt J (1999). The CAD triad hypothesis: a mapping between three moral emotions (contempt, anger, disgust) and three moral codes (community, autonomy, divinity). Journal of Personality and Social Psychology, 76(4), 574–586. doi: 10.1037//0022-3514.76.4.574
Rossi, S., Hallett, M., Rossini, P. M., & Pascual-Leone, A. (2009). Safety, ethical considerations, and application guidelines for the use of transcranial magnetic stimulation in clinical practice and research. Clinical Neurophysiology, 120(12), 2008–2039. doi:10.1016/j.clinph.2009.08.016
Sanfey, A. G. (2003). The Neural Basis of Economic Decision-Making in the Ultimatum Game. Science, 300(5626), 1755–1758.doi:10.1126/science.1082976
Santiesteban, I., Banissy, M. J., Catmur, C., & Bird, G. (2012). Enhancing Social Ability by Stimulating Right Temporoparietal Junction. Current Biology, 22(23), 2274–2277. doi:10.1016/j.cub.2012.10.018
Saver, J. L., & Damasio, A. R. (1991). Preserved access and processing of social knowledge in a patient with acquired sociopathy due to ventromedial frontal damage. Neuropsychologia, 29(12), 1241–1249. doi:10.1016/0028-3932(91)90037-9
Saxe, R., & Kanwisher, N. (2003). People thinking about thinking peopleThe role of the temporo-parietal junction in “theory of mind”. NeuroImage, 19(4), 1835–1842. doi:10.1016/s1053-8119(03)00230-1
Saxe, R. (2006). Uniquely human social cognition. Current Opinion in Neurobiology, 16(2), 235–239.doi:10.1016/j.conb.2006.03.001
Saxe, R. (2016). Moral status of accidents. Proceedings of the National Academy of Sciences, 113(17), 4555–4557.doi:10.1073/pnas.1604154113
Shamsi, F., Hosseini, S., Tahamtan, M., Bayat, M. (2017).The impaired theory of mind in autism spectrum disorders and the possible remediative role of transcranial direct current stimulation. Journal of Advanced Medical Sciences and Applied Technologies, 3(3):175-178. doi.org/10.32598/jamsat.3.3.175
Simonetta-Moreau, M. (2014). Non-invasive brain stimulation (NIBS) and motor recovery after stroke. Annals of Physical and Rehabilitation Medicine, 57(8), 530–542. doi:10.1016/j.rehab.2014.08.003
Sowden, S., Wright, G. R. T., Banissy, M. J., Catmur, C., & Bird, G. (2015). Transcranial Current Stimulation of the Temporoparietal Junction Improves Lie Detection. Current Biology, 25(18), 2447–2451. doi:10.1016/j.cub.2015.08.014
Suter, R. S., & Hertwig, R. (2011). Time and moral judgment. Cognition, 119(3), 454–458. doi:10.1016/j.cognition.2011.01.018
Taylor, R., Galvez, V., & Loo, C. (2018). Transcranial magnetic stimulation (TMS) safety: a practical guide for psychiatrists. Australasian Psychiatry, 26(2), 189–192. doi:10.1177/1039856217748249
Tassy, S., Oullier, O., Duclos, Y., Coulon, O.,Mancini, J., Deruelle, C., Attarian, S., Felician, O., Wicker, B. (2011). Disrupting the right prefrontal cortex alters moral judgement. Social Cognitive and Affective Neuroscience, 7(3), 282–288. doi: 10.1093/scan/nsr008
Tranel, D., & Damasio, H. (1994). Neuroanatomical correlates of electrodermal skin conductance responses. Psychophysiology, 31(5), 427–438. doi:10.1111/j.1469-8986.1994.tb01046.x
Van den Bos, K. (2003). On the Subjective Quality of Social Justice: The Role of Affect as Information in the Psychology of Justice Judgments. Journal of Personality and Social Psychology, 85(3), 482–498. doi:10.1037/0022-3514.85.3.482
Wimmer, H. (1983). Beliefs about beliefs: Representation and constraining function of wrong beliefs in young children’s understanding of deception. Cognition, 13(1), 103–128. doi:10.1016/0010-0277(83)90004-5
Wood, J. N., & Grafman, J. (2003). Human prefrontal cortex: processing and representational perspectives. Nature Reviews Neuroscience, 4(2), 139–147. doi:10.1038/nrn1033
Wout, M. van't, Kahn, R. S., Sanfey, A. G., & Aleman, A. (2005). Repetitive transcranial magnetic stimulation over the right dorsolateral prefrontal cortex affects strategic decision-making. NeuroReport, 16(16), 1849–1852. doi:10.1097/01.wnr.0000183907.08149.
Young, L., Camprodon, J. A., Hauser, M., Pascual-Leone, A., & Saxe, R. (2010). Disruption of the right temporoparietal junction with transcranial magnetic stimulation reduces the role of beliefs in moral judgments. Proceedings of the National Academy of Sciences, 107(15), 6753–6758. doi:10.1073/pnas.0914826107
Young, L., & Saxe, R. (2011). When ignorance is no excuse: Different roles for intent across moral domains. Cognition, 120(2), 202–214. doi:10.1016/j.cognition.2011.04.005
Young, L., & Waytz, A. (2013). Mind attribution is for morality. In S. Baron-Cohen, H. Tager-Flusberg, & M. V. Lombardo (Eds.), Understanding other minds: Perspectives from developmental social neuroscience (p. 93–103). Oxford University Press.
 
 
 
 
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