High levels of innovative technologies, such as the Internet of Things (IoT), cloud computing, and blockchain have been integrated into e-Health systems to mitigate the potential risk of unsatisfactory health management outcomes. The implementation of cloud computing and IoT technologies on e-Health systems has improved diagnostics, treatments, convenience, reduced costs, redundant loss, and enhanced patient outcomes. Users can utilize IoT-cloud e-Health services anytime, anywhere, and in any environment.
The purpose of this study is to create an efficient and secure data management scheme for e-Health systems that utilized cloud computing, IoT, and blockchain technologies to achieve improved security and privacy with low computational forfeits. To guarantee security robustness for e-Health application services, we designed an IoT-cloud-based authentication and access control scheme. The proposed scheme can be effectively executed on low-cost testbeds (Raspberry PI) while ensuring greater security than historically available alternatives. Then, we introduce an interoperability management scheme with certificateless cryptographic primitives for securing cross-chain e-Health transactions. Unlike most existing cross-chain transaction exchanging solutions, we refine the Delegated Proof of Stake (DPoS) consensus algorithm as a verification scheme to ensure the data integrity and provenance of the transferred transactions when performing cross-chain interactions. The scheme relies on cross-chain consensus with relays to improve the compatibility among heterogeneous blockchains. However, system efficiency could be further improved with the future development of more efficient leaner codes, algorithms, and architectures.

Abstract i
Table of Contents ii
List of Tables iv
List of Figures v
Chapter 1 Introduction 1
1.1 Background and Motivation 1
1.2 Research Problems 7
1.3 Notations 15
1.4 Contributions 16
1.5 Outline of the Dissertation 25
Chapter 2 The State of the Art 27
2.1 Innovative e-Health Concepts 28
2.2 Security for e-Health Systems 38
2.3 The State of the Art 39
2.4 Blockchain Technology for e-Health Management Systems 54
Chapter 3. IoT-Cloud-based Solution dealing with Authentication and Access control issues. 61
3.1 The requirement for IoT-cloud-based e-Health Management 63
3.2 Preliminary and Assumption 86
3.3 The proposed scheme 87
3.4 Security Analysis 93
3.5 Proof-of-concept Implementation 102
3.6 Brief Summary 112
Chapter 4. Blockchain-based Solution dealing with Data exchange issues. 115
4.1 System requirement of Cross-blockchain Transactions 115
4.2 Preliminary 118
4.3 The Proposed Scheme 121
4.4 Protocol Analysis 126
4.5 Proof of concept implementation 128
4.6 Brief Summary 132
Chapter 5 Discussion on Other Issues 135
5.1 Resource Management 135
5.2 Context Awareness 138
5.3 Data Privacy 138
5.4. Challenges and Open Issues 147
Chapter 6 Conclusion and Future Work 157
6.1 Conclusion 158
6.2 Future Work 163
References 165

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